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Article

Relevance of polymorphisms in MC4R and BDNF in short normal stature.

BMC pediatrics - 22 Aug 2018

Herrfurth Nikolas, Volckmar Anna-Lena, Peters Triinu, Kleinau Gunnar, Müller Anne, Cetindag Cigdem, Schonnop Laura, Föcker Manuel, Dempfle Astrid, Wudy Stefan A, Grant Struan F A, Reinehr Thomas, Cousminer Diana L, Hebebrand Johannes, Biebermann Heike, Hinney Anke

Abstract excerpt

BACKGROUND: Variation in genes of the leptinergic-melanocortinergic system influence both body weight and height. Because short normal stature (SNS) is characterized by reduced body height, delayed maturation and leanness, allelic variation of genes in this pathway are hypothesized to affect this common condition. METHODS: We analyzed the coding regions of LEP, MC4R, MRAP2 and BDNF in 185 children with SNS...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Melanocortin, Type 4

Source

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Identifiers

PMID: 30134862
DOI: 10.1186/s12887-018-1245-1
PMCID: PMC6106737

Genes

BDNF
LEP
MRAP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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