Article

Genetic risk factors for postoperative complications after major surgery and shared genetic aetiology with non-postoperative phenotypes

2025-12-12

Abstract excerpt

<h4>Background</h4> Up to 15% of patients worldwide experience serious postoperative complications after major surgery. We explored the genetic basis of five common postoperative complications and whether they share genetic aetiology with their non-postoperative equivalents. <h4>Methods</h4> We performed case-control genome-wide association studies (GWAS) using UK Biobank data from >140,000 participants. The pri...

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Literature Corpus work: 02aea05a-1f90-5451-a908-39b9410fc407
DOI: 10.64898/2025.12.11.25342055

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