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Article

Quaternary structural parameters of the congenital cataract causing mutants of αA-crystallin.

Molecular and cellular biochemistry - 1 Mar 2012

Kore Rajshekhar, Hedges Rebecca A, Oonthonpan Lalita, Santhoshkumar Puttur, Sharma Krishna K, Abraham Edathara C

Abstract excerpt

Pediatric cataract of the congenital type is the most common form of childhood blindness and it is clinically and genetically heterogeneous. Mutations in 22 different genes have been identified to be associated with congenital cataracts, and among them, eight mutants belong to αA-crystallin. To explain how mutations in αA-crystallin lead to the development of cataract, quaternary structural parameters, and...

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Identifiers

PMID: 22045060
DOI: 10.1007/s11010-011-1131-8
PMCID: PMC3788686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Quaternary structural parameters of the congenital cataract causing mutants of αA-crystallin.PMID 22045060Read ↗

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