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Article

Tubular cell phenotype in HIV-associated nephropathy: role of phospholipid lysophosphatidic acid.

Experimental and molecular pathology - 1 Aug 2015

Ayasolla Kamesh R, Rai Partab, Rahimipour Shai, Hussain Mohammad, Malhotra Ashwani, Singhal Pravin C

Abstract excerpt

Collapsing glomerulopathy and microcysts are characteristic histological features of HIV-associated nephropathy (HIVAN). We have previously reported the role of epithelial mesenchymal transition (EMT) in the development of glomerular and tubular cell phenotypes in HIVAN. Since persistent tubular cell activation of NFκB has been reported in HIVAN, we now hypothesize that HIV may be contributing to tubular cell...

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Identifiers

PMID: 26079546
DOI: 10.1016/j.yexmp.2015.06.004
PMCID: PMC4527607

Genes

LPA
ILK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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