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Plasma Membrane Proteomic Profile Discovers Macrophage-capping Protein Related to Latent HIV-1

7 May 2019

Abstract excerpt

BACKGROUND: Due to the persistence of latent HIV-infected cellular reservoirs, HIV virus can not be eradicated completely. OBJECTIVE: To identify proteins related to HIV latency, we performed a subcellular proteomic study in HIV latent cell lines. METHODS: An established HIV-1 latent cell model (J-Lat Tat-GFP Clone A7 cells, A7 cells) and its parental cell line (Jurkat cells) were used. The plasma membrane (PM)...

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PMID: 31057110
DOI: 10.2174/1570162x17666190506155222

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