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The Role of DAPK1 in the Cell Cycle Regulation of Cervical Cancer Cells and in Response to Topotecan

1 Jan 2022

Abstract excerpt

Cervical cancer is one of the most serious health conditions, with nearly 500,000 women developing the disease each year worldwide. At present, the treatment of recurrent cervical cancer remains largely ineffective, and efforts in cancer drug development are currently focused on critical serine/threonine kinases, such as death-associated protein kinase 1 (DAPK1) and polo-like kinase 1 (PLK1). In the current...

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PMID: 35154442
DOI: 10.7150/jca.66492

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The Role of DAPK1 in the Cell Cycle Regulation of Cervical Cancer Cells and in Response to TopotecanPMID 35154442Read ↗

The Role of Death-Associated Protein Kinase-1 in Cell Homeostasis-Related ProcessesSemantic proximity Read ↗

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Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function.Semantic proximity Read ↗

Polo-Like Kinases (Plks), a Key Regulator of Cell Cycle and New Potential Target for Cancer TherapySemantic proximity Read ↗

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Polo-like kinase inhibitors: an emerging opportunity for cancer therapeuticsSemantic proximity Read ↗

CIP2A Modulates Cell-Cycle Progression in Human Cancer Cells by Regulating the Stability and Activity of Plk1Semantic proximity Read ↗

A review of Plks: Thinking outside the (polo) boxSemantic proximity Read ↗

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Death-associated protein kinase 1 promotes growth of p53-mutant cancers.Semantic proximity Read ↗

Mitotic syndicates Aurora Kinase B (AURKB) and mitotic arrest deficient 2 like 2 (MAD2L2) in cohorts of DNA damage response (DDR) and tumorigenesisSemantic proximity Read ↗

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