Article
Evolutionary and expression analysis of miR-#-5p and miR-#-3p at the miRNAs/isomiRs levels.
BioMed research international - 1 Jan 2015
Guo Li, Yu Jiafeng, Yu Hao, Zhao Yang, Chen Shujie, Xu Changqing, Chen Feng
Abstract excerpt
We mainly discussed miR-#-5p and miR-#-3p under three aspects: (1) primary evolutionary analysis of human miRNAs; (2) evolutionary analysis of miRNAs from different arms across the typical 10 vertebrates; (3) expression pattern analysis of miRNAs at the miRNA/isomiR levels using public small RNA sequencing datasets. We found that no bias can be detected between the numbers of 5p-miRNA and 3p-miRNA, while miRNAs...
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