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Article

Viral subpopulation diversity in influenza virus isolates compared to clinical specimens.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2015

Rutvisuttinunt W, Chinnawirotpisan P, Thaisomboonsuk B, Rodpradit P, Ajariyakhajorn C, Manasatienkij W, Simasathien S, Shrestha S K, Yoon I K, Klungthong C, Fernandez S

Abstract excerpt

BACKGROUND: Influenza virus (IFV) isolates obtained from mammalian cell cultures are valuable reagents used for vaccine production, antigenic characterization, laboratory assays, and epidemiological and evolutionary studies. Complete genomic comparison of IFV isolates with their original clinical specimens provides insight into cell culture-driven genomic changes which may sequentially alter the virus phenotype....

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PMID: 26071329
DOI: 10.1016/j.jcv.2015.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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