Article

Disparate evolution of virus populations in upper and lower airways of mechanically ventilated patients

2019-01-02

Abstract excerpt

In routine surveillance and diagnostic testing, influenza virus samples are typically collected only from the upper respiratory tract (URT) due to the invasiveness of sample collection from the lower airways. Very little is known about virus variation in the lower respiratory tract (LRT) and it remains unclear if the virus populations at different sites of the human airways may develop to have divergent genetic si...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d3d3ffc1-fcf5-5712-9dd2-1ae07e5c2dd7
DOI: 10.1101/509901

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Disparate evolution of virus populations in upper and lower airways of mechanically ventilated patientsDOI 10.1101/509901Read

Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-ChipSemantic proximity Read

The Dynamics of Influenza A H3N2 Defective Viral Genomes from a Human Challenge StudySemantic proximity Read

Influenza B viruses exhibit lower within-host diversity than influenza A viruses in human hostsSemantic proximity Read

Within-Host Evolution of Human Influenza Virus.Semantic proximity Read

Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification.Semantic proximity Read

Influenza A genomic diversity during human infections underscores the strength of genetic drift and the existence of tight transmission bottlenecksSemantic proximity Read

Influenza B Viruses Exhibit Lower Within-Host Diversity than Influenza A Viruses in Human Hosts.Semantic proximity Read

Stochastic processes dominate the within and between host evolution of influenza virusSemantic proximity Read

Intrahost-diversity of influenza A virus in upper and lower respiratory tract derived samples from a college communitySemantic proximity Read

Parallel evolution of influenza across multiple spatiotemporal scales.Semantic proximity Read

Stochastic processes constrain the within and between host evolution of influenza virus.Semantic proximity Read

Influenza A genomic diversity during human infections underscores the strength of genetic drift and the existence of tight transmission bottlenecksSemantic proximity Read