Article
An investigation of the association between ADRB2 gene polymorphisms and asthma in Kazakh population.
The clinical respiratory journal - 1 Jun 2020
Akparova Almira, Aripova Akmaral, Abishev Meirzhan, Kazhiyakhmetova Baglan, Pirmanova Ainur, Bersimbaev Rakhmetkazhi
Abstract excerpt
INTRODUCTION: Beta-2-adrenergic receptor (ADRB2) is present in the cells of the respiratory tract, including bronchial smooth muscle cells and bronchial epithelium, and is a target for endogenous catecholamines and drugs used to treat the obstructive lung diseases. OBJECTIVES: This study aimed to investigate the possible association of the Arg16Gly and Gln27Glu polymorphisms of the ADRB2 gene with asthma and its...
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