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Article

Cytoplasmic and mitochondrial protein translation in axonal and dendritic terminal arborization.

Nature neuroscience - 1 Jul 2007

Chihara Takahiro, Luginbuhl David, Luo Liqun

Abstract excerpt

We identified a mutation in Aats-gly (also known as gars or glycyl-tRNA synthetase), the Drosophila melanogaster ortholog of the human GARS gene that is associated with Charcot-Marie-Tooth neuropathy type 2D (CMT2D), from a mosaic genetic screen. Loss of gars in Drosophila neurons preferentially affects the elaboration and stability of terminal arborization of axons and dendrites. The human and Drosophila genes...

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PMID: 17529987
DOI: 10.1038/nn1910

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Cytoplasmic and mitochondrial protein translation in axonal and dendritic terminal arborization.PMID 17529987Read ↗

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