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Article

MDM2 beyond cancer: podoptosis, development, inflammation, and tissue regeneration.

Histology and histopathology - 1 Nov 2015

Ebrahim Martrez, Mulay Shrikant R, Anders Hans-Joachim, Thomasova Dana

Abstract excerpt

Murine double minute (MDM)-2 is an intracellular molecule with diverse biological functions. It was first described to limit p53-mediated cell cycle arrest and apoptosis, hence, gain of function mutations are associated with malignancies. This generated a rationale for MDM2 being a potential therapeutic target in cancer therapy. Meanwhile, several additional functions and pathogenic roles of MDM2 have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26062755
DOI: 10.14670/HH-11-636

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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