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Article

Macrophage-derived tumor necrosis factor-α mediates diabetic renal injury.

Kidney international - 1 Oct 2015

Awad Alaa S, You Hanning, Gao Ting, Cooper Timothy K, Nedospasov Sergei A, Vacher Jean, Wilkinson Patrick F, Farrell Francis X, Brian Reeves W

Abstract excerpt

Monocyte/macrophage recruitment correlates strongly with the progression of diabetic nephropathy. Tumor necrosis factor-α (TNF-α) is produced by monocytes/macrophages but the direct role of TNF-α and/or macrophage-derived TNF-α in the progression of diabetic nephropathy remains unclear. Here we t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26061548
DOI: 10.1038/ki.2015.162
PMCID: PMC4589442

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26061548-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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