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Article

Membrane-Associated Transporter Protein (MATP) Regulates Melanosomal pH and Influences Tyrosinase Activity.

PloS one - 1 Jan 2015

Bin Bum-Ho, Bhin Jinhyuk, Yang Seung Ha, Shin Misun, Nam Yeon-Ju, Choi Dong-Hwa, Shin Dong Wook, Lee Ai-Young, Hwang Daehee, Cho Eun-Gyung, Lee Tae Ryong

Abstract excerpt

The SLC45A2 gene encodes a Membrane-Associated Transporter Protein (MATP). Mutations of this gene cause oculocutaneous albinism type 4 (OCA4). However, the molecular mechanism of its action in melanogenesis has not been elucidated. Here, we discuss the role of MATP in melanin production. The SLC45A2 gene is highly enriched in human melanocytes and melanoma cell lines, and its protein, MATP, is located in...

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Identifiers

PMID: 26057890
DOI: 10.1371/journal.pone.0129273
PMCID: PMC4461305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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