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The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target

1 Jan 2015

Abstract excerpt

The canonical Wnt signaling pathway is involved in a variety of biological processes like cell proliferation, cell polarity, and cell fate determination. This pathway has been extensively investigated as its deregulation is linked to different diseases, including various types of cancer, skeletal defects, birth defect disorders (including neural tube defects), metabolic diseases, neurodegenerative disorders and...

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PMID: 26056602
DOI: 10.1186/s40591-015-0038-2

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