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Article

The HEPT Analogue WPR-6 Is Active against a Broad Spectrum of Nonnucleoside Reverse Transcriptase Drug-Resistant HIV-1 Strains of Different Serotypes.

Antimicrobial agents and chemotherapy - 1 Aug 2015

Xu Weisi, Zhao Jianxiong, Sun Jianping, Yin Qianqian, Wang Yan, Jiao Yang, Liu Junyi, Jiang Shibo, Shao Yiming, Wang Xiaowei, Ma Liying

Abstract excerpt

Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are important components of the highly active antiretroviral therapy (HAART) used to treat human immunodeficiency type 1 virus (HIV-1). However, because of the emergence of drug resistance and the adverse effects of current anti-HIV drugs, it is essential to develop novel NNRTIs with an excellent safety profile, improved activity against NNRTI-resistant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26055365
DOI: 10.1128/AAC.00440-15
PMCID: PMC4505209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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