Genetic variant of miR-4293 rs12220909 is associated with susceptibility to non-small cell lung cancer in a Chinese Han population.

doi:10.1371/journal.pone.0175666

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Article

Genetic variant of miR-4293 rs12220909 is associated with susceptibility to non-small cell lung cancer in a Chinese Han population.

PloS one - 1 Jan 2017

Fan Lixia, Chen Linqi, Ni Xiaoling, Guo Shicheng, Zhou Yinghui, Wang Chenji, Zheng Yabiao, Shen Fangyuan, Kolluri Vijay Kumar, Muktiali Merlin, Zhao Zhenhong, Wu Junjie, Zhao Dunmei, He Zhenglei, Feng Xulong, Yuan Ziyu, Zhang Juan, Jin Li, Wang Jiucun, Wang Minghua

Abstract excerpt

Non-small cell lung cancer is one of the most common cancers and the leading cause of cancer death worldwide. Genetic variants in regulatory regions of some miRNAs might be involved in non-small cell lung cancer susceptibility and survival. rs12220909 (G/C) genetic polymorphism in miR-4293 has been shown to be associated with decreased risk of esophageal squamous cell carcinoma. However, the influence of...

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PMID: 28410417
DOI: 10.1371/journal.pone.0175666
PMCID: PMC5391943

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