Article
Diversity of lactase persistence in African milk drinkers.
Human genetics - 1 Aug 2015
Jones Bryony Leigh, Oljira Tamiru, Liebert Anke, Zmarz Pawel, Montalva Nicolas, Tarekeyn Ayele, Ekong Rosemary, Thomas Mark G, Bekele Endashaw, Bradman Neil, Swallow Dallas M
Abstract excerpt
The genetic trait of lactase persistence is attributable to allelic variants in an enhancer region upstream of the lactase gene, LCT. To date, five different functional alleles, -13910*T, -13907*G, -13915*G, -14009*G and -14010*C, have been identified. The co-occurrence of several of these alleles in Ethiopian lactose digesters leads to a pattern of sequence diversity characteristic of a 'soft selective sweep'....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.