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Article

The importance of claudin-7 palmitoylation on membrane subdomain localization and metastasis-promoting activities.

Cell communication and signaling : CCS - 9 Jun 2015

Heiler Sarah, Mu Wei, Zöller Margot, Thuma Florian

Abstract excerpt

BACKGROUND: Claudin-7 (cld7), a tight junction (TJ) component, is also found basolaterally and in the cytoplasm. Basolaterally located cld7 is enriched in glycolipid-enriched membrane domains (GEM), where it associates with EpCAM (EpC). The conditions driving cld7 out of TJ into GEM, which is associated with a striking change in function, were not defined. Thus, we asked whether cld7 serines or palmitoylation...

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Share to Antigens, Neoplasm
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26054340
DOI: 10.1186/s12964-015-0105-y
PMCID: PMC4459675

Genes

GEM
MMP14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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