Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic risk of subsequent esophageal cancer in lymphoma and breast cancer long-term survival patients: a pilot study.

The pharmacogenomics journal - 1 Jun 2016

Boldrin E, Rumiato E, Fassan M, Rugge M, Cagol M, Marino D, Chiarion-Sileni V, Ruol A, Gusella M, Pasini F, Amadori A, Saggioro D

Abstract excerpt

The occurrence of a second primary esophageal carcinoma (EC) in long-term cancer survivors may represent a late effect of previous radio-chemotherapeutic treatment. To identify the genetic factors that could increase this risk, we analyzed nine variants within ERCC1, XPD, XRCC1 and XRCC3 DNA repair pathway genes, and GSTP1, TP53 and MDM2 genes in 61 patients who received radio-chemotherapy for a prior lymphoma or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemoradiotherapy
Share to Esophageal Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Esophageal Squamous Cell Carcinoma

Share to Lymphoma

Share to Neoplasms, Second Primary

Share to Pilot Projects

Share to Survivors

Share to Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 26054330
DOI: 10.1038/tpj.2015.41

Genes

ERCC1
GSTP1
MDM2
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic risk of subsequent esophageal cancer in lymphoma and breast cancer long-term survival patients: a pilot study.PMID 26054330Read ↗

Esophageal cancer: Risk factors, genetic association, and treatment.Semantic proximity Read ↗

Systematic Review and Meta-analysis of the Most Common Genetic Mutations in Esophageal Squamous Cell Carcinoma.Semantic proximity Read ↗

Pharmacokinetics and pharmacogenomics in esophageal cancer chemoradiotherapy.Semantic proximity Read ↗

Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: a review.Semantic proximity Read ↗

Genetic variations in esophageal cancer risk and prognosis.Semantic proximity Read ↗

A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with esophageal squamous cell carcinomaSemantic proximity Read ↗

Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway.Semantic proximity Read ↗

The effect of XPD/ERCC2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis.Semantic proximity Read ↗

Frequent germline mutation in the BRCA2 gene in esophageal squamous cell carcinoma patients from a low-risk Chinese population.Semantic proximity Read ↗

An investigation on the polymorphisms of two DNA repair genes and susceptibility to ESCC and GCA of high-incidence region in northern China.Semantic proximity Read ↗

A functional BRCA1 coding sequence genetic variant contributes to risk of esophageal squamous cell carcinoma.Semantic proximity Read ↗

Potential risk of esophageal squamous cell carcinoma due to nucleotide excision repair XPA and XPC gene variants and their interaction among themselves and with environmental factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.