Article
Pharmacokinetics and pharmacogenomics in esophageal cancer chemoradiotherapy.
Advanced drug delivery reviews - 20 May 2009
Sakaeda Toshiyuki, Yamamori Motohiro, Kuwahara Akiko, Nishiguchi Kohshi
Abstract excerpt
Esophageal cancer is one of the most lethal malignancies. Surgical resection of the tumor from the primary site has been the standard treatment, especially for localized squamous cell carcinoma, but considerable clinical efforts during the last decade have resulted in novel courses of treatment. These options include chemoradiotherapy, consisting of a continuous infusion of 5-fluorouracil (5-FU), cisplatin...
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