Article
Association of TIM4 promoter polymorphism -1419G>A with childhood asthma in a Chinese Han population.
Tissue antigens - 1 Jul 2009
Cai P C, Hu L H, Cui T P, Li Y R, Chen F H, Wu Q W
Abstract excerpt
TIM4, which is expressed on dendritic cells and macrophages, plays an important role in the proliferation of T helper type 2 (Th2) cells. Asthma, as a complex genetic disease, is thought to arise from the development of a Th2-lymphocyte-predominant immune response. To evaluate the effects of the promoter polymorphisms (-1419G>A and -1609G>A) in TIM4 on asthma susceptibility, case-control and family-based...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.