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Article

Genetic variation in the adenosine regulatory cycle is associated with posttraumatic epilepsy development.

Epilepsia - 1 Aug 2015

Diamond Matthew L, Ritter Anne C, Jackson Edwin K, Conley Yvette P, Kochanek Patrick M, Boison Detlev, Wagner Amy K

Abstract excerpt

OBJECTIVE: Determine if genetic variation in enzymes/transporters influencing extracellular adenosine homeostasis, including adenosine kinase (ADK), [ecto-5'-nucleotidase (NT5E), cluster of differentiation 73 (CD73)], and equilibrative nucleoside transporter type-1 (ENT-1), is significantly associated with epileptogenesis and posttraumatic epilepsy (PTE) risk, as indicated by time to first seizure analyses....

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Source

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Identifiers

PMID: 26040919
DOI: 10.1111/epi.13044
PMCID: PMC4523397

Genes

ADK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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