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Article

Genetic variability in glutamic acid decarboxylase genes: associations with post-traumatic seizures after severe TBI.

Epilepsy research - 1 Feb 2013

Darrah Shaun D, Miller Megan A, Ren Dianxu, Hoh Nichole Z, Scanlon Joelle M, Conley Yvette P, Wagner Amy K

Abstract excerpt

Post traumatic seizures (PTS) occur frequently after traumatic brain injury (TBI). Since gamma-amino butyric acid (GABA) neurotransmission is central to excitotoxicity and seizure development across multiple models, we investigated how genetic variability for glutamic acid decarboxylase (GAD) influences risk for PTS. Using both a tagging and functional single nucleotide polymorphism (SNP) approach, we genotyped...

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Source

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Identifiers

PMID: 22840783
DOI: 10.1016/j.eplepsyres.2012.07.006
PMCID: PMC3594692

Genes

PTS
GAD1
GAD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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