Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Etiology matters – Genomic DNA Methylation Patterns in Three Rat Models of Acquired Epilepsy

9 May 2016

Abstract excerpt

This study tested the hypothesis that acquired epileptogenesis is accompanied by DNA methylation changes independent of etiology. We investigated DNA methylation and gene expression in the hippocampal CA3/dentate gyrus fields at 3 months following epileptogenic injury in three experimental models of epilepsy: focal amygdala stimulation, systemic pilocarpine injection, or lateral fluid-percussion induced traumatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Epilepsy research and treatment
Share to Genetics and Neurodevelopmental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27157830
DOI: 10.1038/srep25668

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Etiology matters – Genomic DNA Methylation Patterns in Three Rat Models of Acquired EpilepsyPMID 27157830Read ↗

Molecular Genetics of Acquired Temporal Lobe Epilepsy.Semantic proximity Read ↗

Neuronal and glial DNA methylation and gene expression changes in early epileptogenesis.Semantic proximity Read ↗

Whole transcriptome analysis of the hippocampus: toward a molecular portrait of epileptogenesisSemantic proximity Read ↗

The Epigenetics of Epilepsy and Its ProgressionSemantic proximity Read ↗

Transcriptional Pathology Evolves over Time in Rat Hippocampus after Lateral Fluid Percussion Traumatic Brain InjurySemantic proximity Read ↗

Epileptogenesis: Can the Science of Epigenetics Give Us Answers?Semantic proximity Read ↗

Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injurySemantic proximity Read ↗

Persistent DNA methylation and downregulation of homeostatic genes in astrocytes after pilocarpine-induced status epilepticus: Implications for epileptogenesisSemantic proximity Read ↗

METHYLATION BIOMARKERS ASSOCIATED WITH DRUG-RESISTANT EPILEPSYSemantic proximity Read ↗

High concordance between hippocampal transcriptome of the mouse intra‐amygdala kainic acid model and human temporal lobe epilepsySemantic proximity Read ↗

The methylation hypothesis: Do epigenetic chromatin modifications play a role in epileptogenesis?Semantic proximity Read ↗

Deep sequencing reveals increased DNA methylation in chronic rat epilepsySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.