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Illumina Synthetic Long Read Sequencing Allows Recovery of Missing Sequences even in the "Finished" C. elegans Genome.

Scientific reports - 3 Jun 2015

Li Runsheng, Hsieh Chia-Ling, Young Amanda, Zhang Zhihong, Ren Xiaoliang, Zhao Zhongying

Abstract excerpt

Most next-generation sequencing platforms permit acquisition of high-throughput DNA sequences, but the relatively short read length limits their use in genome assembly or finishing. Illumina has recently released a technology called Synthetic Long-Read Sequencing that can produce reads of unusual length, i.e., predominately around 10 Kb. However, a systematic assessment of their use in genome finishing and...

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PMID: 26039588
DOI: 10.1038/srep10814
PMCID: PMC4650653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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