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Article

Expression and new exon mutations of the human Beta defensins and their association on colon cancer development.

PloS one - 1 Jan 2015

Semlali Abdelhabib, Al Amri Abdullah, Azzi Arezki, Al Shahrani Omair, Arafah Maha, Kohailan Muhammad, Aljebreen Abdulrahman M, Alharbi Othman, Almadi Majid A, Azzam Nahla Ali, Parine Narasimha Reddy, Rouabhia Mahmoud, Alanazi Mohammad S

Abstract excerpt

The development of cancer involves genetic predisposition and a variety of environmental exposures. Genome-wide linkage analyses provide evidence for the significant linkage of many diseases to susceptibility loci on chromosome 8p23, the location of the human defensin gene cluster. Human β-defensins (hBDs) are important molecules of innate immunity. This study was designed to analyze the expression and genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Share to RNA, Neoplasm

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Identifiers

PMID: 26038828
DOI: 10.1371/journal.pone.0126868
PMCID: PMC4454434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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