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Article

Loss of human beta-defensin 1, 2, and 3 expression in oral squamous cell carcinoma.

Oral microbiology and immunology - 1 Oct 2009

Joly S, Compton L M, Pujol C, Kurago Z B, Guthmiller J M

Abstract excerpt

INTRODUCTION: Human beta-defensins (HBDs) are cationic, antimicrobial peptides produced by epithelial cells and involved in various aspects of the innate and acquired immune responses. They are expressed by oral tissues as constitutive and inducible genes. Recently, single nucleotide polymorphisms (SNPs) of beta-defensins have been correlated with increased susceptibility to certain diseases. Studies have...

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Identifiers

PMID: 19702947
DOI: 10.1111/j.1399-302X.2009.00512.x

Genes

HBD
DEFB1

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