Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of Conserved N-Linked Glycans on Ebola Virus Glycoprotein 2.

The Journal of infectious diseases - 1 Oct 2015

Lennemann Nicholas J, Walkner Madeline, Berkebile Abigail R, Patel Neil, Maury Wendy

Abstract excerpt

BACKGROUND: N-linked glycosylation is a common posttranslational modification found on viral glycoproteins (GPs) and involved in promoting expression, cellular attachment, protection from proteases, and antibody evasion. The GP subunit GP2 of filoviruses contains 2 completely conserved N-linked glycosylation sites (NGSs) at N563 and N618, suggesting that they have been maintained through selective pressures....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neutralizing
Share to Chlorocebus aethiops

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ebolavirus

Share to Hemorrhagic Fever, Ebola

Share to Polysaccharides

Share to Vero Cells

Share to Viral Envelope Proteins

Share to Virus Internalization

Source

Open in PubMed Open full text

Identifiers

PMID: 26038399
DOI: 10.1093/infdis/jiv201
PMCID: PMC4564545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of Conserved N-Linked Glycans on Ebola Virus Glycoprotein 2.PMID 26038399Read ↗

Exploitation of glycosylation in enveloped virus pathobiologySemantic proximity Read ↗

Influences of Glycosylation on Antigenicity, Immunogenicity, and Protective Efficacy of Ebola Virus GP DNA VaccinesSemantic proximity Read ↗

The Secret Life of Viral Entry Glycoproteins: Moonlighting in Immune EvasionSemantic proximity Read ↗

Flavivirus Envelope Protein Glycosylation: Impacts on Viral Infection and PathogenesisSemantic proximity Read ↗

Less Is More: Ebola Virus Surface Glycoprotein Expression Levels Regulate Virus Production and InfectivitySemantic proximity Read ↗

Dengue Virus Glycosylation: What Do We Know?Semantic proximity Read ↗

SARS-CoV-2 spike protein receptor-binding domain N-glycans facilitate viral internalization in respiratory epithelial cells.Semantic proximity Read ↗

Defining the impact of Getah virus envelope protein glycosylation site mutations on viral replication, host adaptation, virulence, and immune evasion.Semantic proximity Read ↗

Comparison of N- and O-linked glycosylation patterns of ebolavirus glycoproteinsSemantic proximity Read ↗

Protein <i>N</i> -glycosylation is essential for SARS-CoV-2 infectionSemantic proximity Read ↗

Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA ReplicationSemantic proximity Read ↗

Evolving roles of glycosylation in the tug-of-war between virus and hostSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.