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Article

Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.

Molecular cancer research : MCR - 1 Sept 2015

Hunter John C, Manandhar Anuj, Carrasco Martin A, Gurbani Deepak, Gondi Sudershan, Westover Kenneth D

Abstract excerpt

UNLABELLED: KRAS mutations are the most common genetic abnormalities in cancer, but the distribution of specific mutations across cancers and the differential responses of patients with specific KRAS mutations in therapeutic clinical trials suggest that different KRAS mutations have unique biochemical behaviors. To further explain these high-level clinical differences and to explore potential therapeutic...

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Source

Identifiers

PMID: 26037647
DOI: 10.1158/1541-7786.MCR-15-0203

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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