Article
High-resolution live imaging reveals axon-glia interactions during peripheral nerve injury and repair in zebrafish.
Disease models & mechanisms - 1 Jun 2015
Xiao Yan, Faucherre Adèle, Pola-Morell Laura, Heddleston John M, Liu Tsung-Li, Chew Teng-Leong, Sato Fuminori, Sehara-Fujisawa Atsuko, Kawakami Koichi, López-Schier Hernán
Abstract excerpt
Neural damage is a devastating outcome of physical trauma. The glia are one of the main effectors of neuronal repair in the nervous system, but the dynamic interactions between peripheral neurons and Schwann cells during injury and regeneration remain incompletely characterized. Here, we combine laser microsurgery, genetic analysis, high-resolution intravital imaging and lattice light-sheet microscopy to study...
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