Article
Leveraging large genomic datasets to illuminate the pathobiology of autism spectrum disorders.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2021
Searles Quick Veronica B, Wang Belinda, State Matthew W
Abstract excerpt
"Big data" approaches in the form of large-scale human genomic studies have led to striking advances in autism spectrum disorder (ASD) genetics. Similar to many other psychiatric syndromes, advances in genotyping technology, allowing for inexpensive genome-wide assays, has confirmed the contribution of polygenic inheritance involving common alleles of small effect, a handful of which have now been definitively...
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