Article
A Common Variant in the CDK8 Gene Is Associated with Sporadic Pituitary Adenomas in the Portuguese Population: A Case-Control Study.
International journal of molecular sciences - 4 Oct 2022
Gaspar Leonor M, Gonçalves Catarina I, Fonseca Fernando, Carvalho Davide, Cortez Luísa, Palha Ana, Barros Inês F, Nobre Ema, Duarte João S, Amaral Cláudia, Bugalho Maria J, Marques Olinda, Pereira Bernardo D, Lemos Manuel C
Abstract excerpt
The majority of pituitary adenomas occur in a sporadic context, and in the absence of known genetic predisposition. Three common variants at the NEBL (rs2359536), PCDH15 (rs10763170) and CDK8 (rs17083838) loci were previously associated with sporadic pituitary adenomas in the Han Chinese population, but these findings have not yet been replicated in any other population. The aim of this case-control study was to...
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