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Article

Melatonin-induced suppression of DNA methylation promotes odontogenic differentiation in human dental pulp cells

1 Jan 2020

Abstract excerpt

Differentiation potency of human dental pulp cells (hDPCs) is essential for dentin regeneration. DNA methylation is one of the major epigenetic mechanisms and is suggested to involve in differentiation of hDPCs, the machinery of which includes DNA methyltransferase enzymes (DNMTs) and methyl-CpG-binding domain proteins (MBDs). Our previous study has found that melatonin (MT) promoted hDPC differentiation, but its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32718272
DOI: 10.1080/21655979.2020.1795425

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