Article
FVGWAS: Fast voxelwise genome wide association analysis of large-scale imaging genetic data.
NeuroImage - 1 Sept 2015
Huang Meiyan, Nichols Thomas, Huang Chao, Yu Yang, Lu Zhaohua, Knickmeyer Rebecca C, Feng Qianjin, Zhu Hongtu
Abstract excerpt
More and more large-scale imaging genetic studies are being widely conducted to collect a rich set of imaging, genetic, and clinical data to detect putative genes for complexly inherited neuropsychiatric and neurodegenerative disorders. Several major big-data challenges arise from testing genome-wide (NC>12 million known variants) associations with signals at millions of locations (NV~10(6)) in the brain from...
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