Article
Regional imaging genetic enrichment analysis.
Bioinformatics (Oxford, England) - 15 Apr 2020
Yao Xiaohui, Cong Shan, Yan Jingwen, Risacher Shannon L, Saykin Andrew J, Moore Jason H, Shen Li
Abstract excerpt
MOTIVATION: Brain imaging genetics aims to reveal genetic effects on brain phenotypes, where most studies examine phenotypes defined on anatomical or functional regions of interest (ROIs) given their biologically meaningful interpretation and modest dimensionality compared with voxelwise approaches. Typical ROI-level measures used in these studies are summary statistics from voxelwise measures in the region,...
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