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Article

Functional polymorphisms of interferon-gamma affect pneumonia-induced sepsis.

PloS one - 1 Jan 2014

Wang Ding, Zhong Xuan, Huang Dongjian, Chen Rui, Bai Guibin, Li Qing, Yu Bolan, Fan Yong, Sun Xiaofang

Abstract excerpt

OBJECTIVE: Sepsis is an inflammatory syndrome caused by infection, and both its incidence and mortality are high. Because interferon-gamma (IFN-γ) plays an important role in inflammation, this work assessed IFN-γ single nucleotide polymorphism (SNPs) that may be associated with sepsis. METHODS: A total of 196 patients with pneumonia-induced sepsis and 213 age- and sex-matched healthy volunteers participated in...

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Source

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Identifiers

PMID: 24475220
DOI: 10.1371/journal.pone.0087049
PMCID: PMC3901723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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