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Article

The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation.

PLoS pathogens - 1 May 2015

Friberg Anders, Thumann Sybille, Hennig Janosch, Zou Peijian, Nössner Elfriede, Ling Paul D, Sattler Michael, Kempkes Bettina

Abstract excerpt

Epstein-Barr virus (EBV) is a γ-herpesvirus that may cause infectious mononucleosis in young adults. In addition, epidemiological and molecular evidence links EBV to the pathogenesis of lymphoid and epithelial malignancies. EBV has the unique ability to transform resting B cells into permanently proliferating, latently infected lymphoblastoid cell lines. Epstein-Barr virus nuclear antigen 2 (EBNA-2) is a key...

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Share to Epstein-Barr Virus Nuclear Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immunoprecipitation

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Share to Nuclear Magnetic Resonance, Biomolecular

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Identifiers

PMID: 26024477
DOI: 10.1371/journal.ppat.1004910
PMCID: PMC4449002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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