Article
The papillomavirus E2 DNA binding domain.
Frontiers in bioscience : a journal and virtual library - 1 May 2008
de Prat-Gay Gonzalo, Gaston Kevin, Cicero Daniel O
Abstract excerpt
The DNA binding domain of the E2 master regulator from papillomaviruses is the primary effector for most the essential activities controlled by this protein. In this review we focus on the properties of the DNA binding domain of human papillomavirus strain 16 in solution, integrating structure, dynamics, folding, stability, conformational equilibria, and DNA binding mechanism. We discuss the relevance of these...
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