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The role of the PI3K/Akt/mTOR signalling pathway in human cancers induced by infection with human papillomaviruses

16 Apr 2015

Abstract excerpt

Infection with Human papillomaviruses (HPVs) leads to the development of a wide-range of cancers, accounting for 5% of all human cancers. A prominent example is cervical cancer, one of the leading causes of cancer death in women worldwide. It has been well established that tumor development and progression induced by HPV infection is driven by the sustained expression of two oncogenes E6 and E7. The expression of...

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PMID: 26022660
DOI: 10.1186/s12943-015-0361-x

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