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Signaling pathways in HPV‐associated cancers and therapeutic implications

1 Mar 2015

Abstract excerpt

Human papillomaviruses (HPVs) are small double-stranded circular DNA viruses with 8 kb genomes. So far, more than 150 HPVs have been identified, and 12 types of HPVs have been conclusively linked to cancer by the International Agency for Research on Cancer/World Health Organization. Expression of HPV E5, E6 and E7 oncoproteins can alter multiple signaling pathways to cause cancer. In this review, the signaling...

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PMID: 25752815
DOI: 10.1002/rmv.1823

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