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Article

Role of the Akt/mTOR signaling pathway in human papillomavirus-associated nasal and sinonasal inverted papilloma.

Acta biochimica et biophysica Sinica - 1 Dec 2017

Liu Yongliang, Duan Lihua, Tian Jie, Song Daoliang, Zhang Min, Zhao Shenlin, Yin Zhaofu, Xiang Xinxin, Li Xuezhong

Abstract excerpt

Nasal and sinonasal inverted papilloma (NSIP) is a benign tumor in which surface epithelial cells grow downward into the underlying supportive tissue with varying degrees of metaplasia. Human papillomavirus (HPV) has been proposed as the causal agent in the pathogenesis of this disease. Many studies have shown that HPV can activate the Akt/mechanistic target of rapamycin (mTOR) signaling pathway, but the role of...

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PMID: 29040365
DOI: 10.1093/abbs/gmx108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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