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Article

Cutaneous squamous and neuroendocrine carcinoma: genetically and immunohistochemically different from Merkel cell carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2015

Pulitzer Melissa P, Brannon A Rose, Berger Michael F, Louis Peter, Scott Sasinya N, Jungbluth Achim A, Coit Daniel G, Brownell Isaac, Busam Klaus J

Abstract excerpt

Cutaneous neuroendocrine (Merkel cell) carcinoma most often arises de novo in the background of a clonally integrated virus, the Merkel cell polyomavirus, and is notable for positive expression of retinoblastoma 1 (RB1) protein and low expression of p53 compared with the rare Merkel cell polyomavirus-negative Merkel cell carcinomas. Combined squamous and Merkel cell tumors are consistently negative for Merkel...

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Identifiers

PMID: 26022453
DOI: 10.1038/modpathol.2015.60
PMCID: PMC4920599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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