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DNA methylation markers and serum α-fetoprotein level are prognostic factors in hepatocellular carcinoma

1 Jul 2015

Abstract excerpt

INTRODUCTION: Hypermethylation of relevant genes may affect the prognosis of patients with cancer. The purpose of this study was to analyze whether methylation of the promoter regions of cell cycle regulators as well as elevated α-Fetoprotein (AFP) levels are useful prognostic factors for patients with hepatocellular carcinoma (HCC). MATERIAL AND METHODS: Nested methylation-specific PCR (nested-MSP) was used to...

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Share to Epigenetics and DNA Methylation
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PMID: 26019036
DOI: 10.1016/s1665-2681(19)31171-8

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