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Article

Production of Recombinant Adeno-Associated Virus Vectors

1 May 2005

Abstract excerpt

Recombinant adeno-associated virus (rAAV) is a prototypical gene therapy vector characterized by excellent safety profiles, wide host range, and the ability to transduce differentiated cells. Numerous rAAV-based vectors providing efficient and sustained expression of transgenes in target tissues have been developed for preclinical studies. Interest in rAAV has been driven by advances in production methods...

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Identifiers

PMID: 15916480
DOI: 10.1089/hum.2005.16.551

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