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Molecular design for recombinant adeno-associated virus (rAAV) vector production

4 Dec 2017

Abstract excerpt

Recombinant adeno-associated virus (rAAV) vectors are increasingly popular tools for gene therapy applications. Their non-pathogenic status, low inflammatory potential, availability of viral serotypes with different tissue tropisms, and prospective long-lasting gene expression are important attributes that make rAAVs safe and efficient therapeutic options. Over the last three decades, several groups have...

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PMID: 29204900
DOI: 10.1007/s00253-017-8670-1

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