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Article

Genetic stability of pneumococcal isolates during 35 days of human experimental carriage.

Vaccine - 26 Jun 2015

Gladstone R A, Gritzfeld J F, Coupland P, Gordon S B, Bentley S D

Abstract excerpt

BACKGROUND: Pneumococcal carriage is a reservoir for transmission and a precursor to pneumococcal disease. The experimental human pneumococcal carriage model provides a useful tool to aid vaccine licensure through the measurement of vaccine efficacy against carriage (VEcol). Documentation of the genetic stability of the experimental human pneumococcal carriage model is important to further strengthen confidence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26006086
DOI: 10.1016/j.vaccine.2015.05.021
PMCID: PMC4503797

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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