Article
Ascending contraction and descending relaxation in the distal colon of mice lacking interstitial cells of Cajal.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi - 1 Jun 2005
Okishio Yutaka, Takeuchi Tadayoshi, Fujita Akikazu, Suenaga Kiyotaka, Fujinami Kaori, Munakata Satoru, Takewaki Tadashi, Hata Fumiaki
Abstract excerpt
Recently an essential role of interstitial cells of Cajal (ICC) within myenteric plexus (ICC-MY) was suggested in ascending contraction and descending relaxation in the mouse ileum. The role of ICC in these neural reflexes was examined in the distal colonic segments prepared from the wild type and c-kit mutant, W/W(V) mice, in the present study. Localized distension of the segments from the wild type mice by...
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