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Article

Down-regulation of miR-23b induces phenotypic switching of vascular smooth muscle cells in vitro and in vivo.

Cardiovascular research - 1 Sept 2015

Iaconetti Claudio, De Rosa Salvatore, Polimeni Alberto, Sorrentino Sabato, Gareri Clarice, Carino Annarita, Sabatino Jolanda, Colangelo Maria, Curcio Antonio, Indolfi Ciro

Abstract excerpt

AIMS: Phenotypic switch of vascular smooth muscle cells (VSMCs) plays a key role in the pathogenesis of different vascular diseases, such as atherosclerosis and restenosis after coronary intervention. MicroRNAs have been identified as key regulators of VSMC biology. The miR-23b is highly expressed in VSMCs and it is involved in differentiation, proliferation, and migration of several non-vascular cell types....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Source

Identifiers

PMID: 25994172
DOI: 10.1093/cvr/cvv141

Genes

ACTA2
MYH11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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