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Article

SLCO1B1 polymorphism is not associated with risk of statin-induced myalgia/myopathy in a Czech population.

Medical science monitor : international medical journal of experimental and clinical research - 20 May 2015

Hubáček Jaroslav A, Dlouhá Dana, Adámková Vera, Zlatohlavek Lukáš, Viklický Ondřej, Hrubá Petra, Češka Richard, Vrablík Michal

Abstract excerpt

BACKGROUND: Gene SLCO1B1, encoding solute organic anionic transport polypeptide OATP1B1, belongs to the group of candidates potentially influencing statin treatment safety. OATP1B1 regulates (not only) the hepatic uptake of statins. Its genetic variation was described as an important predictor of statin-associated myopathy in a cohort of patients treated with a maximum dose of simvastatin. However, the impact of...

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Source

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Identifiers

PMID: 25992810
DOI: 10.12659/MSM.893007
PMCID: PMC4450600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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